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1.
Beware of the acute bowel disease in COVID-19 patients.
Lotti, Marco; Giulii Capponi, Michela; Magnone, Stefano; Campanati, Luca; Lucianetti, Alessandro.
ANZ J Surg ; 90(12): 2586-2588, 2020 12.
Article in English | MEDLINE | ID: covidwho-810993

Subject(s)
COVID-19/epidemiology , Cecal Diseases/diagnosis , Cecum/diagnostic imaging , Colonoscopy/methods , SARS-CoV-2 , Tomography, X-Ray Computed/methods , Acute Disease , Aged, 80 and over , Cecal Diseases/epidemiology , Comorbidity , Humans , Male
2.
Colorectal surgery obesity-related morbidity during COVID-19.
Montorfano, Lisandro; Miret, Rafael; Rahman, Asad Ur; Alonso, Mileydis; Maron, David J; Roy, Mayank; Ferri, Francisco; Bejarano, Pablo; Wexner, Steven D.
Surg Obes Relat Dis ; 16(9): 1372-1375, 2020 09.
Article in English | MEDLINE | ID: covidwho-641942

ABSTRACT

Tocilizumab, a monoclonal antiinterluekin-6 receptor antibody, has been empirically used in the treatment of cytokine release syndrome associated with severe coronavirus disease 2019 infections. The efficacy and safety of these medications for these patients is unknown. The purpose of this report was to present a case of acute large bowel perforation in a morbidly obese patient with coronavirus disease 2019 pneumonia who received empiric Tocilizumab. This case report analyzes the risks of acute large bowel perforation after using this medication empirically and discusses the appropriate management of this adverse event.


Subject(s)
Antibodies, Monoclonal, Humanized/adverse effects , Betacoronavirus , Cecal Diseases/etiology , Coronavirus Infections/drug therapy , Intestinal Perforation/etiology , Obesity, Morbid/complications , Pneumonia, Viral/drug therapy , COVID-19 , Cecal Diseases/diagnosis , Cecal Diseases/surgery , Coronavirus Infections/complications , Coronavirus Infections/diagnosis , Cytokine Release Syndrome/etiology , Cytokine Release Syndrome/prevention & control , Female , Humans , Intestinal Perforation/diagnosis , Intestinal Perforation/surgery , Middle Aged , Pandemics , Pneumonia, Viral/complications , Pneumonia, Viral/diagnosis , SARS-CoV-2 , COVID-19 Drug Treatment
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